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TRAF2 Recombinant Rabbit mAb (bsm-62996R)  
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產(chǎn)品編號(hào) bsm-62996R
英文名稱 TRAF2 Recombinant Rabbit mAb
中文名稱 腫瘤壞死因子受體相關(guān)因子2重組兔單抗
別    名 TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3; TRAF2; TRAP3.  
抗體來(lái)源 Rabbit
克隆類型 Recombinant
克 隆 號(hào) 15A5
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,Flow-Cyt=1:20-50,ICC/IF=1:50-200,IP=1:20-50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測(cè)分子量 56
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human TRAF2: 45685 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis.

SWISS:
Q12933

Gene ID:
7186

信號(hào)傳導(dǎo)(Signaling Intermediates) TRAF2在介導(dǎo)細(xì)胞凋亡信號(hào)及在腫瘤細(xì)胞的凋亡中發(fā)揮著一定的作用。TRAF2分布較廣泛,在所有檢測(cè)的組織中都有表達(dá),包括心臟、腦、脾臟、肺、肝、骨骼肌、腎和睪丸等,TRAF2可以介導(dǎo)TNFRII、CD40、CD30和EV病毒轉(zhuǎn)化蛋白LMP1活化NF-kB。
產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with TRAF2 monoclonal antibody, unconjugated (bsm-62996R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Cervical Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAF2 Monoclonal Antibody, Unconjugated (bsm-62996R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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