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MRP7 Rabbit pAb (bs-5761R)  
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產品編號 bs-5761R
英文名稱 MRP7 Rabbit pAb
中文名稱 多藥耐藥相關蛋白7抗體
別    名 ABCC10; ATP binding cassette, sub family C(CFTR/MRP), member 10; ATP binding cassette, subfamily C, member 10; ATP-binding cassette sub-family C member 10; EST182763; mFLJ00002; MRP7; MRP7_HUMAN; Multidrug resistance associated protein 7; Multidrug resistance-associated protein 7; SIMRP7; SIMRP7.  
研究領域 腫瘤  免疫學  信號轉導  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 162 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MRP7/ABCC10.: 1401-1492/1492 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.

Function:
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.

Similarity:
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.

SWISS:
Q5T3U5

Gene ID:
89845

Database links:

Entrez Gene: 89845 Human

Omim: 612509 Human

SwissProt: Q5T3U5 Human

Unigene: 55879 Human



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