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ZMIZ2 Rabbit pAb (bs-4391R)  
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產(chǎn)品編號 bs-4391R
英文名稱 ZMIZ2 Rabbit pAb
中文名稱 鋅指MIZ結構域蛋白2抗體
別    名 2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2; Zinc finger MIZ type containing 2; zinc finger, MIZ-type containing 2; zinc finger, MIZtype containing2; ZMIZ 2; Zmiz2; ZMIZ2_HUMAN.  
研究領域 轉錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 97 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZMIZ2: 1-100/920 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]

Function:
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.

Subcellular Location:
Nucleus. Detected at replication foci throughout S phase.

Tissue Specificity:
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary.

Similarity:
Contains 1 SP-RING-type zinc finger.

SWISS:
Q8NF64

Gene ID:
83637

Database links:

Entrez Gene: 83637 Human

Entrez Gene: 52915 Mouse

Entrez Gene: 289783 Rat

Entrez Gene: 6378 Rat

Omim: 611196 Human

SwissProt: Q8NF64 Human

SwissProt: Q8CIE2 Mouse

Unigene: 600681 Human

Unigene: 77978 Human

Unigene: 1144 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (bs-4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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