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Rabbit Anti-SOX1/Gold Conjugated antibody (bs-12276R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@www.mm3000.cn
訂購QQ:  400-901-9800
技術支持:techsupport@www.mm3000.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12276R-Gold
英文名稱 Rabbit Anti-SOX1/Gold Conjugated antibody
中文名稱 膠體金標記的核轉錄因子抗體
別    名 sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SOX-1; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 發(fā)育生物學  神經(jīng)生物學  干細胞  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Pig, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human SOX6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
Transcriptional activator.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mainly expressed in the developing central nervous system.

Post-translational modifications:
Sumoylation inhibits the transcriptional activity.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 6656 Human

Entrez Gene: 20664 Mouse

Omim: 602148 Human

SwissProt: O00570 Human

SwissProt: P53783 Mouse

Unigene: 202526 Human

Unigene: 39088 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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